20 ha Farm in Caledon with top quality arable grain land.
Centrally located in the heart of the Overberg, halfway between Caledon and Napier and in close proximity of Riviersonderend (N2) and Stanford. But still far enough for total rest and peace. A separate fence surrounds the rustic brick house which boasts 4 bedrooms, 2 bathrooms, large living room with big braai/fireplace, open plan kitchen, pantry and scullery, 3 garages and a basement. The living room with a stacking door and the bedrooms with sliding doors, open onto the veranda with breathtaking views. The farm is completely fenced and has 2 camps, which are ideal for livestock, each with a water point.
Outside sheds to house animals. Solar electricity and geyser.
Municipal water, sufficient for household and animal use. 300-600 mm rainfall per year.
The private school Rûens College is only 18 km away and Rietpoel Overberg Agri 10 km.
20 ha Farm in Caledon with top quality arable grain land.
Centrally located in the heart of the Overberg, halfway between Caledon and Napier and in close proximity of Riviersonderend (N2) and Stanford. But still far enough for total rest and peace. A separate fence surrounds the rustic brick house which boasts 4 bedrooms, 2 bathrooms, large living room with big braai/fireplace, open plan kitchen, pantry and scullery, 3 garages and a basement. The living room with a stacking door and the bedrooms with sliding doors, open onto the veranda with breathtaking views. The farm is completely fenced and has 2 camps, which are ideal for livestock, each with a water point.
Outside sheds to house animals. Solar electricity and geyser.
Municipal water, sufficient for household and animal use. 300-600 mm rainfall per year.
The private school Rûens College is only 18 km away and Rietpoel Overberg Agri 10 km.
A dose of healthy bacteria could give women the upper hand in ridding themselves of a common but annoying vaginal infection, a new clinical trial reports.
Women treated with Lactin-V – an experimental vaginal suppository containing live bacteria – were much more likely to end their recurring bouts of bacterial vaginosis than women treated with a placebo, the researchers said.
“What we’re doing essentially is knocking down the bad bacteria and then replacing the good bacteria, allowing them to grow and keep at bay the bad bacteria as part of an optimal balance,” explained lead researcher Dr Craig Cohen, a professor of obstetrics, gynaecology and reproductive sciences at the University of California, San Francisco.
Bacterial vaginosis (BV) is the most common vaginal condition in women aged 15 to 44, affecting nearly 30% of women of reproductive age in the United States, researchers said in background notes.
Antibiotic therapy
Every vagina is colonised with different strains of bacteria, Cohen said. Vaginosis occurs when “bad” bacteria overwhelm the normal “good” bacteria.
Symptoms include a thin white or grey vaginal discharge, itching or burning of the vagina, and a strong fishlike odour, according to the US Centers for Disease Control and Prevention.
The condition also increases the risk of premature birth or low birth weight among newborns, as well as upping a woman’s risk of contracting HIV and other sexually transmitted diseases, the CDC says.
Standard therapy is to treat the infection with a six-month course of a topical antibiotic gel called metronidazole, said Dr Taraneh Shirazian, director of global women’s health at New York University’s School of Global Public Health.
As Cohen and his team see it, there’s a problem with that standard therapy. Once the antibiotic therapy is done, there’s nothing to prevent the bad bacteria from overwhelming the vaginal microbiome again.
Because of that, as many as 75% of women have their infection recur within three months of treatment, researchers said.
“They’re doing what their provider recommends, they’re taking antibiotics, and even though they’re doing that, it’s coming back,” Cohen said.
Recurrent infections
In the study, 228 women who were diagnosed with bacterial vaginosis were treated with a five-day course of metronidazole gel. Two-thirds of those women were then assigned to receive Lactin-V for 11 weeks.
Lactin-V is a powder that women self-administer with a vaginal applicator. It contains Lactobacillus crispatus, a strain of bacteria that naturally occurs in the vagina. This bacteria produces lactic acid, which inhibits the growth of bad bacteria.
By the end of the initial three months, 30% of women in the Lactin-V group had experienced recurrence of their infection, compared with 45% of women in the placebo group, results showed.
“Essentially, it’s associated with a 34% reduced risk of recurrence during that 12-week time period,” Cohen said.
The women were tracked out for six months total, and those who received Lactin-V continued to do better, Cohen said.
“We also found approximately 80% of women who were in the Lactin-V arm were successfully colonized with Lactobacillus crispatus, the actual strain we tested,” Cohen said.
The findings were published on 14 May in the New England Journal of Medicine.
Shorter therapy
Shirazian said this new treatment looks promising, given that it took three months as opposed to the standard treatment of six months. Currently, women apply antibiotic gel for seven days, then twice weekly for six months to treat recurring bacterial vaginosis.
“That’s a lot shorter, which is advantageous,” said Shirazian, who wasn’t part of the study. “It’s hard to continue a therapy for six months. It’s hard to maintain it.”
However, Shirazian said future trials of Lactin-V would produce stronger results if they compare the new treatment against the current standard therapy as well as placebo.
Researchers are discussing proceeding to stage three clinical trials with the maker of Lactin-V, California-based Osel, Inc., Cohen said. There’s currently no timeline for getting the new treatment to market.
“I know there are a lot of women suffering from BV, and this product is not available now. It’s a long timeline to go through the drug approval process with the [US Food and Drug Administration],” Cohen said.
Quality and Production Controller Wheat reporting to the Operations Manager
• Grade 12
• Full Spectrum Grain Grading
• GMF Qualification
• Minimum of 5 years’ experience
• Valid Driver’s Licence with own reliable transport
• Experience in Team Management Operational Agility
• Human Resources
• Strong problem solving
• Ensure Vision, Mission and Values underpin all activities
• OHSA, ISO and HACCP systems
• Must be able to read, write, speak and understand English Must be found medical fit by Occupational Medical Practitioner for job appointed for. APPLY with full detailed Cv and recent photo to fs@generico.co.za
As a C# developer, you will gain exposure to cloud-based products and international clients within an Agile environment. Collaborate with your colleagues over a game of golf, catching a wave or during braai Fridays. Live your best life working on some exciting projects within the financial industry.
Reference number for this position is RS48319 which is a permanent position based in Cape Town offering a cost to company salary of R1.2m per annum negotiable on experience and ability. Contact Rylene on
or call her on 011 463 3633 to discuss this and other opportunities.
Are you ready for a change of scenery? E-Merge IT Recruitment is a specialist niche recruitment agency. We offer our candidates options so that we can successfully place the right developers with the right companies in the right roles. Check out the E-Merge website for more great positions.
Candidates are required to have eight years’ experience in C#, with 3 years’ exclusively in Agile methodologies including Scrum and Kanban. Other areas of expertise include:
CSS
HTML
Asp.Net
Azure
LINQ
MVC
JavaScript
AJAX
SQL
Duties and responsibilities
Design, develop and test code that adheres to the company standard
Exercise Azure DevOps to manage tasks and application code
Work collaboratively with colleagues to ensure clarity and understanding on requirements
Provide estimates on project delivery
Qualification
BSc computer science
Candidates are required to have eight years’ experience in C#, with 3 years’ exclusively in Agile methodologies including Scrum and Kanban. Other areas of expertise include:
CSS
HTML
Asp.Net
Azure
LINQ
MVC
JavaScript
AJAX
SQL
Duties and responsibilities
Design, develop and test code that adheres to the company standard
Exercise Azure DevOps to manage tasks and application code
Work collaboratively with colleagues to ensure clarity and understanding on requirements
Women who drink a lot of sodas, sweetened juices and other sugary drinks are at greater risk of developing heart disease, a new study finds.
Those who drink one or more a day have nearly a 20% higher risk than women who never do. And it’s not just soda that’s problematic: Fruit drinks with added sugars are also a culprit, researchers say.
Though the study does not prove cause and effect, researchers suspect there are several reasons sugar can increase heart disease risk, according to lead author Cheryl Anderson, interim chair of Family and Public Health at the University of California, San Diego.
“It raises glucose levels and insulin concentrations in the blood, which may increase appetite and lead to obesity, a major risk factor for cardiovascular disease,” she said in a news release from the Journal of the American Heart Association, where the study was published on 13 May.
Different types of drinks
“In addition, too much sugar in the blood is associated with oxidative stress and inflammation, insulin resistance, unhealthy cholesterol profiles and type 2 diabetes, conditions that are strongly linked to the development of atherosclerosis, the slow narrowing of the arteries that underlies most cardiovascular disease,” Anderson noted.
More than 100 000 female teachers in California took part in the study.
Those who drank one or more sugary drinks a day were 26% more likely to need surgery such as angioplasty to restore blood flow and 21% more likely to have a stroke, compared with women who rarely or never drank sugary beverages.
Differences were also found in the type of drinks consumed.
Water is best
Those who drank one or more sugar-sweetened fruit drinks a day had a 42% higher risk of heart disease than women who seldom or never consumed sugary beverages. Those who drank sweetened soda every day had a 23% higher risk of heart disease.
Women who consumed the most sugar-sweetened drinks were more likely to be younger, smokers, obese and less likely have a healthy diet, the researchers found.
Diet soda is sometimes seen as an alternative for people trying to cut back on sugary drinks. But diet drinks contain artificial sweeteners such as saccharin, aspartame, sucralose and others that also have been associated with health risks.
Water is the most accessible and healthy drink, according to the American Heart Association. It has no sugar, no artificial sweeteners and no calories.
An awesome opportunity to join a leading fintech environment whilst working from the comfort of your own home. You will get the opportunity of working across the business engaging with developers, operations staff, data scientists, architects and business constituents to develop and enhance their big data service.
APPLY NOW to join an awesome team and take your career to the next level.
The reference number for this position is GZ49467. This is a 12-month contract to be renewed with the business based in Cape Town (although remote for the foreseeable future), offering a contract rate of R750 per hour negotiable on experience and ability. Contact Garth on
or call him on 011 463 3633 to discuss this and other opportunities.
Are you ready for a change of scenery? E-Merge IT Recruitment is a specialist niche recruitment agency. We offer our candidates options so that we can successfully place the right developers with the right companies in the right roles. Check out the E-Merge website for more great positions.
Do you have a friend who is a developer or technology specialist? We pay cash for successful referrals!
Requirements
Java is absolutely critical for this role
Python will also be highly beneficial
Some Kafka
WEB API’s
Angular
RESTful services
Experience with Elastic Search and Kibana
UI charting (D3/HighCharts/etc.)
Experience with material design is a plus
Attention to detail for UI design
Experience and knowledge on CI/CD and tooling used – Bamboo, Jenkins GIT, Team City, Octopus deploy
Key responsibilities:
Strong programming skills. Experienced and technically strong UI developer (Java, Angular) that is backend (Java) savvy
Development and deployment of data applications
Must be a clear methodical thinker with good problem-solving skills
Able to perform under pressure in a fast-changing environment
Design and Implementation of infrastructure tooling and work on horizontal frameworks and libraries
Background in computer science, engineering, physics, mathematics or equivalent
Worked on Big Data platforms (Vanilla Hadoop, Cloudera or Hortonworks
Java is absolutely critical for this role
Python will also be highly beneficial
Some Kafka
WEB API’s
Angular
RESTful services
Experience with Elastic Search and Kibana
UI charting (D3/HighCharts/etc.)
Experience with material design is a plus
Attention to detail for UI design
Experience and knowledge on CI/CD and tooling used – Bamboo, Jenkins GIT, Team City, Octopus deploy
Key responsibilities:
Strong programming skills. Experienced and technically strong UI developer (Java, Angular) that is backend (Java) savvy
Development and deployment of data applications
Must be a clear methodical thinker with good problem-solving skills
Able to perform under pressure in a fast-changing environment
Design and Implementation of infrastructure tooling and work on horizontal frameworks and libraries
Background in computer science, engineering, physics, mathematics or equivalent
Worked on Big Data platforms (Vanilla Hadoop, Cloudera or Hortonworks
Do you have 2+ yearsâ Pay Prop or similar package experience? Looking for a fresh start and want to join a top notch Property Investment Company â Northern Suburbs?
Here is your chance! They are looking for a Residential Rental Portfolio Administrator who can manage 400 properties to join their dynamic team.
EMPLOYMENT TYPE: PERMANENT
SECTOR: Property
START DATE: T.B.C
DUTIES:
– Obtaining monthly levies and rates accounts
– Drafting of lease documentation
– Loading tenants, owners, etc. on PayProp
– Invoicing water accounts on PayProp
– Create payments on Payprop
– Filing
– Debit orders
– Updating rental agents on lease expiries, etc.
– Sending welcome letters to new tenants
– Sending vacating checklist to leaving tenants
– Phoning tenants for non-payment and reporting back to investors
– Letters of demand
– Eviction liaisons between attorneys and investors
– Mail shots to tenants
– Registration of cell-to-gate with property managers
– Lease period extension and negotiations applicable
– Investors monthly recons
– Client liaison
– Rental assist recons and payments
– Mooi River (Tenrisk), Xpello and Rent Guaranteed claims and record keeping
If you’ve not heard back from us within 10 working days, please consider your application as unsuccessful for this role. We will retain your credentials for future similar roles.
Procurement Analyst in Kwazulu-Natal | FMCG Retail | Job Mail | 4811738
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A junior administrative role has arisen in the Group for a multi-skilled, high impact and performanceoriented analytical administrator.
The Procurement Analyst ensures the effective delivery of procurement services in the company. He or she analyses and interprets the financial rules and regulations, procurement policies and guidelines and provides solutions to complex issues related to Procurement. She or he promotes a collaborative client focused quality and results oriented approach in the Department by providing timely and meaningful reports.
MINIMUM REQUIREMENTS
A Diploma or junior Degree in Supply Chain Management with Accounting as a Subject
Alternatively, a Commercial Diploma and/or junior Degree with Accounting as a Subject
Carrying excess pounds can be painful, literally. A new study finds that being overweight or obese ups the risk of pain in people with musculoskeletal disorders.
“Pain, osteoarthritis and weight share a complicated relationship,” said study author Dr Diana Higgins. She’s a researcher with the VA Boston Healthcare System and Boston University School of Medicine.
“Overall, the more weight a patient with a musculoskeletal disorder carries, the more likely they are to report experiencing pain, which may affect functioning and quality of life,” Higgins said in a VA news release.
Researchers analysed data on nearly two million US veterans with musculoskeletal disorders, such as non-traumatic joint disorder; arthritis; low back, back or neck pain.
Strongest in arthritis patients
Overall, 58% said they had pain. Nearly eight in 10 patients were overweight or obese. The higher a patient’s body mass index (BMI), the more likely they were to report pain. BMI is an estimate of body fat based on weight and height.
Compared to those of normal weight, those with moderate obesity (BMI of 35 to 39) were 9% more likely to report pain. And those with severe obesity (BMI of 40 or higher) were 23% more likely.
The connection between excess weight and increased risk of pain was strongest in patients with arthritis, with 40% of overweight patients and 55% of severely obese patients reporting pain.
The association between weight and pain was less pronounced in patients with back or low back pain, according to the study. The results were published recently in the journal Pain Medicine.
While the study shows a link between weight and pain in arthritis patients, further research is needed to understand this relationship, the authors said.
Strain on the joints from excess weight could lead to arthritis pain, but that relationship might also go the other way, they suggested. Pain caused by arthritis could cause patients to avoid physical activity, which could result in a higher BMI.
